| Symbol | DNA BindDom | Species | Pvalue (T Test) | T Score | Logo |
|---|---|---|---|---|---|
|
PPARG |
Hormone-nuclear Receptor Family |
Homo sapiens | 3.61e-32 | 12.12 |
|
|
FOXD1 SRY FOXD3 FOXF2 |
Forkhead Domain Family High Mobility Group (Box) Family Forkhead Domain Family Forkhead Domain Family |
Homo sapiens | 1.63e-11 | 6.69 |
|
|
PAX2 |
Homeodomain Family |
Homo sapiens | 5.28e-10 | 6.14 |
|
|
NR2F1 |
Hormone-nuclear Receptor Family |
Homo sapiens | 3.98e-05 | 3.96 |
|
|
ZEB1 |
BetaBetaAlpha-zinc finger Family |
Homo sapiens | 1.80e-03 | 2.92 |
|
|
PAX6 |
Homeodomain Family |
Homo sapiens | 1.81e-01 | 0.91 |
|
|
TP53 |
Loop-Sheet-Helix Family |
Homo sapiens | 3.97e-01 | 0.26 |
|
BETA: Motif Analysis
Motif Scan on the TF Target Genes
Part1: Up Target Genes
Part2: Down Target Genes
| Symbol | DNA BindDom | Species | Pvalue (T Test) | T Score | Logo |
|---|---|---|---|---|---|
|
PPARG |
Hormone-nuclear Receptor Family |
Homo sapiens | 7.07e-61 | 16.93 |
|
|
PAX2 |
Homeodomain Family |
Homo sapiens | 7.40e-14 | 7.43 |
|
|
NR2F1 |
Hormone-nuclear Receptor Family |
Homo sapiens | 4.03e-09 | 5.78 |
|
|
FOXF2 FOXD3 SRY FOXD1 |
Forkhead Domain Family Forkhead Domain Family High Mobility Group (Box) Family Forkhead Domain Family |
Homo sapiens | 8.68e-04 | 3.13 |
|
|
SPIB |
Ets Domain Family |
Homo sapiens | 1.10e-01 | 1.23 |
|
|
PAX5 |
Homeodomain Family |
Homo sapiens | 2.47e-01 | 0.69 |
|
|
IRF2 |
Interferon Regulatory Factor |
Homo sapiens | 3.77e-01 | 0.31 |
|
Part3: UP vs DOWN Motif Scan
| Symbol | DNA BindDom | Species | Pvalue (T Test) | T Score | Logo |
|---|---|---|---|---|---|
|
FOXF2 FOXD3 SRY |
Forkhead Domain Family Forkhead Domain Family High Mobility Group (Box) Family |
Homo sapiens | 2.28e-05 | -4.24 |
|
|
TBP |
TATA box-binding Family |
Homo sapiens | 8.56e-02 | -1.72 |
|
|
PPARG |
Hormone-nuclear Receptor Family |
Homo sapiens | 1.28e-01 | -1.52 |
|
|
RFX3 |
RFX Domain Family |
Homo sapiens | 1.51e-01 | 1.44 |
|
|
ELK1 ETV3 |
Ets Domain Family Ets Domain Family |
Homo sapiens | 1.73e-01 | 1.36 |
|
|
PAX2 |
Homeodomain Family |
Homo sapiens | 2.23e-01 | -1.22 |
|
|
ZEB1 |
BetaBetaAlpha-zinc finger Family |
Homo sapiens | 2.54e-01 | -1.14 |
|
|
NR2F1 |
Hormone-nuclear Receptor Family |
Homo sapiens | 2.73e-01 | 1.10 |
|
|
PAX6 |
Homeodomain Family |
Homo sapiens | 3.20e-01 | -0.99 |
|
|
MEF2A |
MADS Box Family |
Homo sapiens | 3.28e-01 | 0.98 |
|
|
FOXD1 |
Forkhead Domain Family |
Homo sapiens | 3.95e-01 | 0.85 |
|
|
PAX5 |
Homeodomain Family |
Homo sapiens | 4.96e-01 | -0.68 |
|
|
MYCN TCF12 |
Helix-Loop-Helix Family Helix-Loop-Helix Family |
Homo sapiens | 5.32e-01 | 0.63 |
|
|
CTCF |
BetaBetaAlpha-zinc finger Family |
Homo sapiens | 8.72e-01 | 0.16 |
|
|
TP53 |
Loop-Sheet-Helix Family |
Homo sapiens | 9.54e-01 | -0.06 |
|
|
REL |
Rel Homology Region Family |
Homo sapiens | 9.93e-01 | 0.01 |
|
Part4: Up VS Non Target Motif
| Symbol | DNA BindDom | Species | Pvalue (T Test) | T Score | Logo |
|---|---|---|---|---|---|
|
NR2E3 |
Hormone-nuclear Receptor Family |
Homo sapiens | 2.80e-02 | 2.20 |
|
|
FOXD1 FOXD3 |
Forkhead Domain Family Forkhead Domain Family |
Homo sapiens | 3.21e-02 | 2.15 |
|
|
PAX6 |
Homeodomain Family |
Homo sapiens | 5.38e-02 | 1.93 |
|
|
NFIC |
Nuclear Factor I-CCAAT-binding Transcription Factor (NFI-CTF) Family |
Homo sapiens | 2.82e-01 | 1.08 |
|
|
PAX2 |
Homeodomain Family |
Homo sapiens | 2.95e-01 | 1.05 |
|
|
REL |
Rel Homology Region Family |
Homo sapiens | 3.41e-01 | 0.95 |
|
|
TP53 |
Loop-Sheet-Helix Family |
Homo sapiens | 4.11e-01 | 0.82 |
|
|
PAX5 |
Homeodomain Family |
Homo sapiens | 4.51e-01 | 0.75 |
|
|
PLAG1 |
BetaBetaAlpha-zinc finger Family |
Homo sapiens | 8.78e-01 | 0.15 |
|
Part5: Down VS Non Target Motif
| Symbol | DNA BindDom | Species | Pvalue (T Test) | T Score | Logo |
|---|---|---|---|---|---|
|
FOXF2 SRY FOXD1 FOXD3 |
Forkhead Domain Family High Mobility Group (Box) Family Forkhead Domain Family Forkhead Domain Family |
Homo sapiens | 1.96e-06 | 4.77 |
|
|
PAX6 |
Homeodomain Family |
Homo sapiens | 4.22e-04 | 3.53 |
|
|
PAX2 |
Homeodomain Family |
Homo sapiens | 4.54e-03 | 2.84 |
|
|
PAX5 |
Homeodomain Family |
Homo sapiens | 6.03e-02 | 1.88 |
|
|
ZEB1 |
BetaBetaAlpha-zinc finger Family |
Homo sapiens | 1.63e-01 | 1.40 |
|
|
REL |
Rel Homology Region Family |
Homo sapiens | 2.62e-01 | 1.12 |
|
|
PPARG |
Hormone-nuclear Receptor Family |
Homo sapiens | 3.45e-01 | 0.94 |
|